EXAMINATION OF INTERNAL METABOLOME AND VOCS PROFILE OF BREWERY YEAST AND THEIR MUTANTS PRODUCING BEER WITH IMPROVED AROMA

Examination of internal metabolome and VOCs profile of brewery yeast and their mutants producing beer with improved aroma

Abstract Volatile organic compounds (VOCs) are metabolites pivotal in determining the aroma of various products.A well-known VOC producer of industrial importance is Saccharomyces cerevisiae, partially responsible for flavor of beers and wines.We identified VOCs in beers produced by yeast strains characterized by improved aroma obtained in UV-induc

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A phase 2 study of combined chemo-immunotherapy with cisplatin-pembrolizumab and radiation for unresectable vulvar squamous cell carcinoma

Abstract Background Unresectable or metastatic vulvar cancer has relatively poor outcomes despite chemotherapy-sensitized radiation therapy and combination cytotoxic therapy.Despite the virus-associated and immunogenic nature of this disease, novel immunotherapy options new belial model that exploit this advantage are currently lacking.Platinum age

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